There is no such thing as “which one is better”, the indications of these two drugs are different, and the therapeutic effects are also different. Patients should follow the doctor’s instructions, according to the condition of the choice of appropriate and effective drugs. Escitalopram oxalate tablets are antidepressants. Used in the treatment of depressive disorders, treatment of panic disorder with or without square phobia. Duloxetine Hydrochloride Enteric Capsules, is a psychotropic drug. It is used in the treatment of depressive disorders and in the treatment of generalized anxiety disorder. Adverse effects of escitalopram oxalate tablets may include insomnia, drowsiness, dizziness, constipation, vomiting, dry mouth and other gastrointestinal reactions. Duloxetine hydrochloride enteric capsule general adverse reactions dizziness, nausea, headache and so on. Escitalopram oxalate tablets and duloxetine hydrochloride enteric capsules have no absolute advantages and disadvantages, it is recommended that the patient under the guidance of the doctor to choose the appropriate medication for treatment, do not blindly use the drug, so as not to cause adverse effects.