Rash after polio vaccination can be observed continuously, if there is an aggravation, then you need to seek medical attention. Rash after polio vaccination belongs to the category of normal adverse reactions. It is generally mild and should be observed continuously without special treatment; it can subside within 3 to 5 days and will not have a serious effect on the vaccine effect or your health. However, if the symptoms continue to worsen, accompanied by severe itching and other manifestations, it is necessary to consult a doctor in a timely manner. Under the guidance of a doctor, relevant tests such as blood tests should be performed, and antihistamines such as loratadine should be used to control the progression of symptoms. However, the use of drugs need to be in accordance with the doctor’s instructions, not the use of prescription drugs.