Pain in the bone next to the tailbone can be treated with general treatment, physical therapy, medication and surgery according to the cause of the pain. Common causes include trauma, ankylosing spondylitis, tumors and perianal diseases. 1. Trauma: Trauma may cause tailbone fracture or dislocation, causing pain due to irritation to the surrounding soft tissues. Local braking and rest are needed, and if necessary, the dislocated tailbone can be reset by anal manipulation. Oral non-steroidal anti-inflammatory drugs, such as ibuprofen, can also be taken to reduce the local inflammation and alleviate the symptom of pain in the bone next to the tailbone. 2. Ankylosing spondylitis: it may be caused by genetic, infectious, immune and other factors, and may present with the symptoms of tailbone pain, accompanied by morning stiffness. It can be treated with oral painkillers such as celecoxib and anti-rheumatic drugs such as methotrexate; ultrasound, infrared and other physical therapy methods can also be taken to promote blood circulation, accelerate the absorption of inflammation and relieve symptoms. 3. Tumor: it may be caused by tumor, if there is a local mass causing nerve compression, it will cause pain in the bone next to the tailbone. If it is benign tumor and critical tumor, surgical resection is the mainstay. For malignant tumors, in addition to surgical treatment, chemotherapy, radiotherapy, immunotherapy and other methods are usually needed to reduce the pain symptoms. 4. Perianal diseases: such as perianal abscess, etc., there will be symptoms such as pain in the bone next to the tailbone, which can be alleviated by performing incision and drainage of perianal abscess. There are other causes of pain next to the tailbone, if the persistence of non-relief should be timely consultation, improve the examination to clarify the cause of the disease, follow the doctor’s instructions for treatment, do not self-medication, so as not to delay the condition.