[History taking].
1, mostly between 20-40 years of age onset, slightly more women than men.
2, the disease can be acute or slow.
3, the first symptoms vary depending on the structure involved, such as: visual acuity g for optic nerve damage, weakness in one or more limbs for damage to the pyramidal tract, sensory abnormalities for damage to the posterior cord or spinal thalamic tract, etc..
4, spatial multiple involvement of multiple unrelated sites.
5, temporal multiple remissions alternating with relapses and recurrent attacks.
6, triad of Charcot (Charcot) ataxia, dysarthria and intentional tremor occurring simultaneously.
7, those showing only symptoms of optic neuritis and myelitis, called optic neuritis (Devic’s disease).
8, the progression of the disease is mostly slow, in remission – relapse type, a small number of progressive or acute type (worsening type).
Physical examination
1, systemic examination to note the presence of systemic complications or comorbidities.
2.Specialist examination
1) Fundus examination.
2）Inter-nuclear ophthalmoplegia and rotational nystagmus are highly suggestive of the disease.
(3) Focal signs in more than 2 unrelated parts of the central nervous system.
Ancillary tests
1.Laboratory examination of cerebrospinal fluid, immunological examination, etc.
2. Instrumental examination of evoked potentials; CT or MRI
Differential diagnosis
1.Brain and spinal cord tumor
2, cerebrovascular disease.
3.Brain stem lesion.
Treatment principles
1, the acute period pay attention to bed rest, the usual combination of work and rest, establish confidence, pay attention to the prevention and control of complications, etc..
2, immunosuppressants; hormones, gammaglobulin plasma cross-chemotherapy method neurotrophic drugs.
3, physical therapy and functional exercise.
4, symptomatic treatment.
5, counseling services, regular review.