Interstitial pulmonary fibrosis is a serious disease in respiratory medicine, and its course and prognosis vary depending on the cause and the pathology of interstitial fibrosis, but the overall prognosis is poor. In the early stage, when the symptoms are not severe, some patients can improve and prolong their survival by finding the cause and treating it actively. However, in patients with interstitial lung of unknown etiology, especially idiopathic pulmonary fibrosis, although the disease can be temporarily controlled with treatment, fewer patients have long-term stability and the disease continues to progress, usually over a period of 2-4 years. A small number of patients have a life expectancy of only about 6-12 months due to acute exacerbations. The late stage of interstitial pulmonary fibrosis is mostly due to severe infection, and uncorrectable respiratory failure and clinical death, so when interstitial pulmonary fibrosis occurs should be taken seriously, actively cooperate with the treatment, quit smoking, some patients can still moderately prolong their survival.