The difference between raw and ripened diabetes is the difference in drug categorization, properties, meridians, efficacy and main treatment. For example, Shengdi is a heat-clearing and blood-cooling (relieving blood-heat by clearing heat) medicine, and Ruidi Huang is a blood tonic. Shengdi, sweet, bitter and cold in nature, belongs to the heart, liver and kidney meridians and has the effects of clearing heat and cooling blood, nourishing yin and generating body fluid. Radix Rehmanniae Praeparata should be used in treating various bleeding symptoms caused by heat entering the camp and blood (heat evil invading the body to a deep extent and with more severe symptoms), such as spotting and epistaxis (spitting out blood and nosebleed); treating yin deficiency and internal heat, bone vapor and labor heat, thirst due to injury of body fluids, and constipation caused by yin deficiency and dryness of intestines. Radix Rehmanniae Praeparata (熟地黄), sweet, pungent and warm in nature, belongs to the liver and kidney meridians and has the effect of tonifying blood and nourishing yin, benefiting essence and filling in marrow. Radix Rehmanniae Praeparata treats various symptoms of blood deficiency, such as blood stasis due to blood deficiency, menstrual irregularity, amenorrhea, dysmenorrhea; abdominal pain due to deficiency and cold, bruises and injuries, and it can treat paralysis caused by wind-cold; constipation caused by dryness of intestines due to blood deficiency, and so on. The use of the raw ground ripened rhizome, need to be taken under the guidance of a doctor to identify the evidence, to avoid taking on their own as a tonic, to avoid the medicine is not the right evidence, resulting in adverse consequences.