Hepatic steatosis is often caused by excessive fat intake and metabolic disorders, such as obesity, diabetes mellitus, and hepatitis. It is believed that hepatic steatosis cells are unevenly distributed within the lobules for various reasons, but usually first involve the three zones of the hepatic alveoli, and as the disease worsens, it gradually involves the zone of the alveoli and is focally distributed. According to the diameter of fat droplets in hepatocytes, hepatocellular steatosis can be classified as microvesicular as well as macrovesicular. The former can be an early manifestation, and the formation of microvesicular fat droplets in hepatocytes also represents the metabolic function of hepatocytes, especially the mitochondrial dysfunction. If the degree of steatosis increases, it can cause fatty liver and liver function damage, and if it continues to develop, serious manifestations such as cirrhosis can occur.