Stage 1 Nephropathy usually refers to chronic kidney disease stage 1, which needs to be treated with symptomatic medication after the cause is clarified, such as you can take antihypertensive medication, such as Benadryl and Irbesartan tablets, as well as hypoglycemic medication, such as Metformin, and so on. Chronic kidney disease stage 1 has many causes, mainly including primary kidney disease and secondary kidney disease. The drug treatment varies with different causes. 1. Primary kidney disease: including glomerulonephritis, nephrotic syndrome and other diseases, you can follow the doctor’s prescription ACEI/ARB drugs to reduce urinary protein such as Benadryl, Irbesartan tablets and so on. These drugs can reduce proteinuria, lower blood pressure, can effectively delay the deterioration of renal function. 2. Secondary factors: such as diabetic nephropathy, hypertensive nephropathy, etc. If the chronic kidney disease is caused by diabetes mellitus, you can follow the doctor’s advice to use metformin, acarbose, insulin and other hypoglycemic drugs. Hypertension, on the other hand, apply antihypertensive drugs, such as Benadryl and other antihypertensive drugs. In addition, it is usually necessary to control sodium intake, high-quality low-protein diet, usually can eat milk, lean meat and other high-quality protein. It is recommended that patients with chronic kidney disease stage 1 should go to the hospital in time and take appropriate medication for their condition under the guidance of the doctor.