Irbesartan combined with amlodipine is a common combination drug regimen for the treatment of hypertension, which should start with a small dosage and be gradually adjusted by the doctor according to the blood pressure control. Irbesartan commonly used dosage forms include capsules, tablets, dispersions, etc. The dosage may vary among different dosage forms and specifications. For Irbesartan capsules/ Irbesartan tablets, the recommended starting dose is 150mg once a day; for Irbesartan dispersible tablets, the usually recommended initial and maintenance dose is 150mg per day.Amlodipine is commonly available in tablets, drops and capsules, and the starting dose is usually 2.5mg once a day when used in combination with Irbesartan. Irbesartan may cause dizziness, fatigue, hyperkalemia, and is contraindicated in pregnant and lactating women, and in those who are allergic to the components of this drug; amlodipine’s adverse reactions include headache, ankle edema, fatigue, nausea, abdominal pain, etc. Note that it is contraindicated in patients with severe hypotension, severe aortic stenosis, and allergy to dihydropyridines or to any of the components of this drug. When combining Irbesartan and Amlodipine in the treatment of hypertension, the medication should be used in strict compliance with the doctor’s instructions, and the medication should be taken on time and in accordance with the dosage, and should not be omitted or overdosed, in order to avoid affecting the therapeutic effect or causing adverse consequences. At the same time, blood pressure should be monitored regularly and the medication regimen should be changed under the guidance of the doctor. In daily life, you should also adhere to a long-term low-salt, low-oil and low-sugar diet, and eat more fruits and vegetables as well as coarse grains and cereals.