Reflux esophagitis can be treated with a combination of medications. This disease is suitable for a combination of acid suppressants and gastric stimulants. If medication is not effective, surgery is needed. Reflux esophagitis is due to the reflux of gastric contents and duodenal fluid into the esophagus, resulting in gastric acid and other stimulation of the esophagus, causing esophageal inflammatory reaction. Therefore, this disease needs omeprazole to inhibit acid and reduce the stimulation of gastric acid, together with gastric power drugs such as domperidone or mosapride to reduce reflux. A combination of both types of drugs is suitable. Mucosal protective agents such as magnesium aluminum carbonate can also be used. Reflux esophagitis usually requires surgical treatment, such as anti-reflux surgery and laparoscopic fundoplication, when medication is ineffective or when there is a tendency for malignant changes. In short, reflux esophagitis needs regular hospital consultation and standardized treatment under the guidance of doctors.