Isotretinoin soft capsule is still useful for acne, for most patients, taking isotretinoin soft capsule 2-4 weeks to see the first effect, usually need 15-20 weeks to have obvious effect. Isotretinoin soft capsules are retinoic acid preparations, mainly used for the treatment of severe refractory nodular acne. It can inhibit the activity of sebaceous glands, shrink sebaceous gland tissues, greatly reduce sebum secretion, which in turn reduces the keratinization of skin epithelial cells appearing, and effectively inhibits the growth and reproduction of Propionibacterium acnes. However, there are many adverse reactions to taking Isotretinoin Soft Capsules, such as edema, palpitations, arthralgia and so on after using the drug. It is contraindicated for pregnant women, patients with hepatic or renal insufficiency, and patients with vitamin A overdose. Patients should consult their doctors when taking Isotretinoin Soft Capsules to avoid other side effects caused by overdose.