Sleeping with swollen eyes may be due to infection, allergies, kidney disease, etc., according to the different causes, the treatment is different. 1. Bacterial infection of the blepharoplasty gland causes acute blepharitis, also known as granuloma, manifested as redness, swelling and pain, it is recommended to use local antibiotic eye drops such as tobramycin, levofloxacin, etc., and should be incised and drained after the abscess has matured. 2. Allergy to pollen, mites, etc., causing eyelid soft tissue congestion and edema, it is recommended to remove the allergen immediately, if necessary, use antiallergic drugs such as olopatadine hydrochloride, sodium cromoglycate, etc., and in severe cases, oral antihistamines such as chlortetracycline. 3. Systemic diseases such as nephritis, nephrotic syndrome, etc. due to impaired kidney function, resulting in fluid retention, eye edema, it is recommended to carry out a detailed systemic examination to clarify the cause of the disease, oral diuretics to relieve symptoms. If your eyes are swollen when you sleep, you can apply cold compresses, and if the symptoms are not relieved after a period of time, it is recommended that you consult a doctor as soon as possible. The medication should be used in accordance with the doctor’s instructions, and should not be used blindly on its own.