Most breast cancer patients have few clinical symptoms in the early stage, and a few of them do not even have any specific manifestations, and can only be detected during routine physical examination or breast cancer screening. Therefore, there are fewer signs that can be used as a basis for judgment, and there are not as many as 15, which can be roughly divided into the following categories: 1. nipple overflow: non-pregnant female patients have milk-like liquid in the nipple, usually thin in texture, color is mostly colorless, milky white or yellowish, a few patients may have pus or oozing blood liquid; 2. nipple shape change: the invasion of tumor will cause the milk duct to become shorter, pulling the nipple to the side of the tumor The specific manifestation is nipple retraction, flattening or even invagination; 3. Abnormal breast augmentation: when the lump reaches a certain volume, a hard lump can be touched inside the breast, and as the tumor gradually increases, the breast will show local augmentation; 4. Skin changes: when the tumor invades Cooper’s ligament, the breast skin will appear depression, and when the cancer cells block the lymphatic vessels, the skin will appear edema, showing “Some inflammatory breast cancers may also lead to redness, swelling, roughness and fever; 5. Axillary lymph node enlargement: cancer cells may metastasize to the lymph nodes, resulting in enlargement of the lymph nodes on the same side of the axilla. In addition, patients may suffer from weight loss, weakness, loss of appetite and chest tightness. However, it should be noted that the above symptoms are not criteria for diagnosing breast cancer, but only for the patient’s preliminary judgment at home. To confirm the diagnosis, patients need to go to the hospital for physical examination, breast ultrasound, mammogram, enhanced MRI, etc.