When transaminases are 300 U/L, infusion therapy may not work immediately, and it usually takes 1 week for the transaminases to decrease, and the amount of decrease needs to be judged according to the cause of the transaminase elevation, etc., so it is not possible to make a generalization. For elevated aminotransferases caused by cholecystitis, cholangitis, drug-induced hepatitis, fatty liver, etc., the aminotransferases may drop to the normal range within 7 days after application of hepatoprotective drugs. However, for transaminase elevation caused by autoimmune hepatitis, primary liver cancer, cirrhosis, etc., it is sometimes difficult to reduce transaminase significantly by simply using liver-protecting drugs, and it can only be reduced to a certain value without continuous improvement. At this time, antiviral drugs and drugs to improve liver fibrosis should also be used. Due to the different physical condition of patients, the infusion time needs to be judged by the doctor according to the actual condition of the patient. The above drugs should be used under the guidance of a doctor.