A positive sialoglucosidase indicates the possibility of bacterial vaginosis and it is advisable to diagnose and treat it in conjunction with clinical symptoms. Sialoglucosidase is an enzyme produced by bacteria in the vagina and a value of more than 7 IU/ml can confirm the diagnosis of bacterial vaginosis. Under normal circumstances, a large number of pathogenic microorganisms can survive in the vagina, interdependent and mutually restrained, keeping a certain amount of each other, so they do not cause morbidity. However, if the immunity of the organism is low and the ecological balance of the vagina is disturbed, the dominant pathogenic bacteria can multiply and cause vaginal inflammation. Sialoglucosidase is produced by Gardnerella and anaerobic bacteria, and the type of pathogenic bacteria infecting can be determined by testing the level of sialoglucosidase. Bacterial vaginitis is also associated with an increase in the amount of vaginal discharge, which is thin with a distinct fishy odor, and can be treated with metronidazole suppositories.