Levofloxacin hydrochloride and levofloxacin have the same efficacy, and there are only minor differences in their chemical formulas, which are the same for use in perianal abscesses. Levofloxacin hydrochloride and levofloxacin are the same in terms of indications, contraindications and adverse reactions. Both are mainly used clinically for infectious diseases caused by sensitive bacteria, and one of them can be used to control infection in perianal abscess. Its adverse reactions are fever, dizziness, headache, etc. It is forbidden for those who are allergic to quinolones, pregnant and lactating women, and patients under 18 years old. In addition to medication, perianal abscesses are mainly treated with surgical methods, and the commonly used surgical methods include incision and drainage, one-time radical surgery, incision and drainage, etc. The treatment should be carried out under the guidance of a physician according to the condition. Under the guidance of the physician should be in accordance with the condition of the choice of appropriate treatment program, not blindly take medication, so as not to delay the condition.