At present, itching of the urethra and pain in urination, first of all, we should consider the possible existence of urinary tract infection, such as urethritis, but also consider whether there is glansitis. It is recommended to review the urine routine several times, if necessary, check the routine of prostate fluid, if it is for men, this should also be concerned about. In addition, if necessary, check the color ultrasound of the urinary tract. If all of these tests are normal, it is important to consider what may be the problem? Neurogenic urinary frequency, neurogenic urinary sensitivity. Also, consider the possibility of a bacterial culture and, if necessary, a drug sensitivity test following a urine bacterial culture. Based on the test results, a comprehensive evaluation will be done to determine the diagnosis and treatment plan.