The injection dose of glucagon varies from person to person, and how much more than 20U in 1 shot needs to be determined by the patient’s condition. Glycine insulin is a long-acting insulin analog used for diabetes requiring insulin therapy, and should be administered by subcutaneous injection once a day at the same time to achieve steady-state blood concentrations 2~4 days after the first injection. The injection dose of glucagon should be gradually adjusted according to the patient’s body weight, fasting blood glucose, sensitivity to insulin, pancreatic islet function and tolerance to blood glucose lowering. If the patient applies glycemic insulin 20U patients with good glycemic control, it is not much, if the patient has hypoglycemia, the dosage needs to be adjusted under the guidance of the doctor. In the process of use, attention should be paid to monitoring blood glucose to avoid hypoglycemia (diabetic patients with blood glucose lower than 3.9mmol/L, mostly accompanied by dizziness, panic, sweating and other symptoms) or hypoglycemic reaction (blood glucose is not lower than 3.9mmol/L, but dizziness, panic, sweating and other symptoms), and adjust the dosage according to the blood glucose situation. It is prohibited for those who are allergic to insulin. In addition, patients are advised to pay attention to diet control, appropriate exercise and weight control, and if necessary, combined with oral hypoglycemic drug therapy under the guidance of a doctor.