The hot and cold air of air conditioning can cause the brain blood vessels to dilate and contract respectively. Whether contraction or expansion, it is disturbing the normal equilibrium state of the brain, so there is a possibility of headache. For this case, you need to turn off the air conditioner first and go to a room with a more suitable temperature. If you do not use medication, you can sleep for a while, and after sleeping, most of the patients may be able to relieve the pain. If it is not relieved, it is recommended to use sedative drugs and then rest to let the cerebral blood vessels return to a normal state. If it is still not relieved, you can use symptomatic non-steroidal anti-inflammatory drugs, which have a suppressive effect on the pain center. Try not to blow the air conditioner excessively in normal times. If the pain cannot be relieved by the above methods, promptly seek medical attention. Because excessive blowing of air conditioning may cause organic changes in the brain, promptly go to a tertiary care hospital for a comprehensive diagnosis of organic problems after the doctor’s interview and the auxiliary tests that need to be done.