Asthma attacks are characterized by wheezing accompanied by shrugging of the shoulders. At present, there are about 300 million asthma patients worldwide and about 30 million asthma patients in China. Asthma is an important disease that affects people’s physical and mental health. Many survey data show that the prevalence rate of relatives of asthma patients is higher than that of the group. Environmental factors also play an important contributing role in the development of asthma. What are the causes of shrugging and wheezing? 1, genetic factors: many survey data show that the prevalence of asthma patients’ relatives is higher than the group prevalence, and the closer the kinship, the higher the prevalence, the more serious the patient’s condition, the higher the prevalence of their relatives. The genes associated with asthma are not yet fully understood, but some studies have shown that there are multiple loci of genes associated with allergic diseases. These genes play an important role in the development of asthma. 2.Infection: Asthma formation and attacks are associated with recurrent respiratory infections, most commonly rhinovirus, followed by influenza virus, parainfluenza virus, respiratory syncytial virus and coronavirus. 3, allergens: dust mites are the most common allergens and are important factors in the development of asthma worldwide. There are four common species, namely house dust mite, dust mite, house dust mite and polychaete mite. House dust mites are the most predominant mite in persistent humid climates. Fungi are also one of the allergens present in the indoor air, commonly Penicillium, Aspergillus and Streptomyces. Pollen and grass pollen are the most common outdoor allergens that cause asthma attacks. Woody plants (tree pollen) often cause spring asthma, while grass pollen of grass plants often cause asthma in autumn. 4, climate change: when the temperature, humidity, air pressure and air ions and other changes can trigger asthma, so in the cold winter or autumn and winter climate change more onset. 5, smoking: cigarette smoke (including passive smoking) is the main source of indoor triggering factors, is an important asthma triggering factor, especially for those children with asthma whose parents smoke, often caused by smoking asthma attacks.