The most common clinical condition is corns, usually on the outside of the big toe, which suddenly appears as a distinct hard nodule with pain. Corns are caused by repeated pressure and friction on the skin of the foot, resulting in a thickening of the cuticle. It occurs on the outside of the big toe, the outside of the little toe, and the back of the toe, where it is easily pressed and rubbed repeatedly. However, there are also patients who develop visible hard bumps next to the big toe, which may be caused by localized bacterial infection. Therefore, patients should never easily determine what disease they have simply by virtue of having hard bumps. If you can’t tell the difference, it’s best to visit a dermatologist at a regular hospital for assistance with diagnosis and symptomatic treatment.