Sacral nerve root cysts are a common clinical condition in which patients often present with painful numbness in the lumbosacral region or even in the legs, and some even experience urinary and fecal dysfunction. The traditional treatment method is to bite open the bones of the vertebral plate from behind to reveal the nerve roots, and then surgically remove the cyst. This method often requires a surgical incision of more than 10 cm, which results in a lot of bleeding and often requires intraoperative and postoperative blood transfusion. The recovery period after surgery is long, and if the tumor is large and needs to bite away more bones causing a decrease in sacral strength, it often takes about 3 weeks to gradually return to work; although the surgical excision is generally more thorough, there is still a possibility of cyst recurrence after surgery. In addition, in some cases, the cyst hides in the front or side of the sacrum, which can cause more trouble for surgical exposure of the cyst. Professor Shao Zengwu, head of the bone tumor group of the Hubei Orthopaedic Society and professor of the Department of Orthopaedics at Concordia, has been applying CT-guided percutaneous puncture injection of bioprotein gel to treat sacral cysts since 2006 and has achieved satisfactory results. This is a minimally invasive treatment method: the site of the cyst is determined by CT scan before surgery, the puncture needle is inserted into the cyst through the vertebral plate, and the bioprotein gel is injected after aspiration of the cyst fluid. The entire procedure is controlled within one hour, no surgical incision is made only a needle-eye size puncture needle entrance, no blood transfusion is considered, no bones are bitten and no structural stability of the spine is destroyed, no direct exposure of nerves is required, and no serious cerebrospinal fluid leak has been found so far. After the fluid inside the capsule is extracted by puncture, the cyst space is occupied by filling with bioprotein gel, blocking the cyst passage and preventing cerebrospinal fluid from entering the cyst cavity; the cyst cavity is occluded by postoperative fibroblast proliferation causing adhesions, thus achieving the purpose of gradually making the cyst smaller or disappearing. The method can also reduce the tension and pressure of the nerve fibers on the surface of the cyst and relieve the symptoms of nerve compression. The whole procedure is less invasive, safe and efficient, enabling such minimally invasive treatment even for cases where conventional surgery is difficult with cysts located in front of the sacrum. The data of hundreds of cases successfully treated by Prof. Shao in the past four years show that the majority of patients have obvious improvement of symptoms after surgery and can return to work sooner. The treatment of sacral cysts with CT-guided percutaneous bioprotein gel injection has the advantages of small trauma, safety and reliability, precise efficacy, short hospitalization time and low cost.