Patients who are inadvertently bitten by ladybugs may have different clinical symptoms depending on the severity of the bite. If a patient is bitten by ladybug to a lesser extent, there may be only mild localized skin redness, swelling, pain, itching and other symptoms. The local pain symptoms can be gradually relieved after 2-3 days in most patients and will not cause serious impact on the human body. If the patient is bitten by ladybug to a greater extent and severity, there can be localized elevated skin temperature, obvious swelling of the limbs, severe pain, and in severe cases, chills, high fever and other symptoms of systemic toxicity. Local ultrasound examination should be improved, and if subcutaneous fluid and pus accumulation is found, surgical excision of subcutaneous tissue is required to drain the fluid and strengthen anti-infection treatment, and local inflammation and pain can be gradually relieved in some patients in a week or so.