Purulent nasal mucus and pus sputum are usually caused by an infection of the upper respiratory tract resulting in a purulent infection of the nasopharynx or pharynx, most of which are accompanied by nasal congestion, runny nose, and a sore throat, and need to be treated with antibiotics. For nasal infections, the more commonly used antibiotics are penicillin or cephalosporin antibiotics, which can be treated with amoxicillin clavulanate potassium or cefadroxil. In addition, cough and phlegm medications, such as aminoterol oral solution or eucalyptus-pinene softgel capsules, are also needed. If accompanied by headache, dizziness, weakness, it is likely to be sinusitis caused by yellow phlegm in the nasal cavity, then the first thing to do is to go for a CT examination of the sinuses, to confirm that there is no sinusitis. If there is indeed sinusitis, in addition to the use of the above antibiotics for treatment, but also need to carry out nasal cleaning, you need to go to the ear, nose and throat department to let the doctor to operate, chronic sinusitis recurrent episodes of sinus need to be performed sinus open surgery.