Perianal abscess nodules can be treated by physical therapy, medication or surgery. 1. Physical therapy: warm water sitz bath and local physical therapy can promote local blood circulation, accelerate the absorption of inflammatory exudate, which can help perianal abscess nodule subside. 2. Drug therapy: you can use amoxicillin, levofloxacin, cefixime and other antibacterial drugs for anti-infective treatment, if the condition is serious, intravenous cefuroxime, ciprofloxacin and other antibiotics, can promote the inflammation to subside, so that the hardness of perianal abscess to accelerate the subsidence. 3. Surgery: Conservative treatment is ineffective, and perianal abscess has a sense of fluctuation, you can take surgical treatment, under local anesthesia to carry out abscess incision and drainage, which will help the anal abscess subside, and regular medication change treatment. Patients with hardened perianal abscesses should go to the hospital in time for timely treatment and timely relief of the pain caused by the disease.