If you find swollen lips after waking up, it is possible that the inflammatory edema is caused by a local allergic reaction. It is possible that the allergic reaction is caused by contact with allergy-prone substances such as quilts or pillows that appear to be allergic while sleeping. In addition to the lips, if the face or even the eyelids appear swollen and accompanied by itching, it is determined to be an allergic reaction. In this case, you can take your own oral anti-allergy medication, commonly used drugs such as loratadine or cetirizine, both of which are available in pharmacies. If these two medications do not eliminate the condition, you must go to the dermatology department of the hospital. If necessary, intramuscular diphenhydramine anti-allergy or intravenous glucocorticoid anti-inflammatory and anti-allergic treatment must be administered.