Headache caused by cerebral vasodilation is a vascular headache and can be treated with direct analgesic drugs, commonly used are nonsteroidal antipyretic analgesics such as ibuprofen, naproxen, acetochlorfenac, and also depot tablets. However, the cause of the disease should also be treated. If other contraindications are excluded, strong vasoconstrictive drugs such as sumatriptan and zolmitriptan can be used directly, but it should be noted that these drugs have large side effects and may cause pharmacological hypertension, and some patients may also cause vasoconstriction of the distal limb, which can lead to ischemic necrosis of the limb in severe cases. Also consider the intravenous use of dehydrating agents, cerebral vasodilatation leading to headache often has increased intracranial pressure, the use of dehydrating agents such as mannitol, glycerol fructose, furosemide or sodium heptaerythroside, can reduce intracerebral pressure, reduce intracerebral edema and relieve pain.