Three weeks after a history of high-risk exposure, antibodies are detected with a high degree of accuracy, allowing for a basic determination of HIV infection. According to official data released by the National Center for Disease Control and Prevention (NCDC), the detection rate of the third-generation HIV antibody test kit (collagen gold assay) is 84% in the third week after a history of high-risk exposure. after HIV invades the human body, it will quickly activate the body’s immune system to produce corresponding antibodies, but the time of antibody production varies among individuals, so the window period for detection of HIV varies from three weeks to three months. The detection rate of HIV antibodies is higher in the third week after a history of high-risk exposure, but a negative test at this time does not completely confirm the absence of HIV infection. It can also be combined with HIV-RNA testing to determine whether infection is present, and it is recommended that patients be tested several times during the fourth, sixth, eighth, and twelfth weeks. Consultation with a physician is recommended for further treatment.