Patients with thrombosed hemorrhoids, anal sinusitis, and anal fissure have strong pain during rectal fingerprinting; colonoscopy is not painful if they are under anesthesia. Generally speaking, there will be discomfort during rectal fingerprinting, which is normal, but there will be no obvious pain. However, some patients will have severe pain, such as thrombosed hemorrhoids, anal sinusitis, anal fissure and other conditions, so such a situation can be considered to suspend the rectal fingerprinting. Before the colonoscopy, if you choose to perform the examination under general anesthesia, there is no pain. When the examination is over, some discomfort may occur due to the withdrawal of the anesthetic, but it is a normal phenomenon and can generally be tolerated. If the colonoscopy is performed under awake conditions, there may be some discomfort due to the movement of the colon driven by the colonoscope, but it can often be tolerated.