Levetiracetam can be taken to reduce fever, but it needs to be used under a doctor’s supervision. Levetiracetam is primarily used as an add-on treatment for partial seizures in adults and children over the age of 4. Antipyretics are nonsteroidal anti-inflammatory drugs, such as ibuprofen and acetaminophen. They are used for fever, headache, and joint pain. There are generally no contraindications to taking levetiracetam and fever-reducing medications at the same time, so it is possible to combine them. Adverse reactions that may occur after taking Levetiracetam include symptoms such as drowsiness, fatigue, dizziness, moodiness and loss of appetite. It is contraindicated in those who are allergic to the ingredients of this product. Adverse reactions from taking NSAIDs include nausea, sweating, abdominal pain, and pallor. A very small number of patients may experience granulocyte deficiency, thrombocytopenia, etc. It is contraindicated in severe hepatic or renal insufficiency or hypersensitivity to the product. It is recommended that patients go to the doctor’s guidance, to avoid unauthorized use of the adverse reactions caused by