Buttock flesh pain generally refers to soft tissue pain in the buttocks. Possible causes include trauma, pyriformis syndrome, lumbar disc herniation, and soft tissue sarcoma of the buttocks. 1. Trauma: the buttocks are hit by violence or fall when the buttocks land can cause buttock soft tissue injury and pain, patients usually have a clear history of trauma. 2. Piriformis syndrome: Piriformis syndrome is a series of symptoms caused by compression of the sciatic nerve in the buttocks due to various reasons, such as pain in the buttocks, posterior lateral thighs, lateral calves, difficulty in walking, claudication and so on, and a striated or soft tissue mass may be detected in the buttocks on palpation. 3. Lumbar disc herniation: When lumbar disc herniation compresses the lumbar nerve root at the back, it can cause radiating pain in the lower limbs, which radiates along the buttocks, posterior lateral thighs and lateral calves to the distal end, and it can be accompanied by limited lumbar movement, abnormal sensation in the lower limbs and decreased muscle strength. 4. Soft tissue sarcoma of buttock: infiltration or compression of soft tissue sarcoma of buttock can also cause soft tissue pain of buttock, and soft tissue mass can be detected locally during examination. It is recommended that the patient should go to the hospital as soon as possible to find out the cause of the pain, and then take corresponding treatment measures to treat it.