Chemotherapy regimens and limitations of lymphoma

  What are the chemotherapy regimens for lymphoma?  Chemotherapy is a form of treatment that uses chemical drugs to kill tumor cells, inhibit their growth and reproduction, and promote their differentiation. Over the past 30 years, doctors have developed a number of chemotherapy regimens with proven efficacy, which are important tools in the treatment of lymphoma: In the treatment of Hodgkin’s lymphoma, the ABVD regimen (Adriamycin, Bleomycin, Vincristine, Azelnimine) is preferred, and the MOPP regimen (Azelnimycin, Vincristine, Methylphenidate, Prednisone) is also commonly used.  The CHOP (cyclophosphamide, adriamycin, vincristine, prednisone) regimen and the CHOEP (cyclophosphamide, adriamycin, vincristine, pedialyte glycosides, prednisone) regimen are commonly used in the treatment of non-Hodgkin’s lymphoma.  What are the limitations of chemotherapy for lymphoma?  The limitations of chemotherapy are due to its non-specific cytotoxicity, which is commonly referred to as the “enemy of my enemy”.  The efficacy of chemotherapeutic drugs on lymphoma cells is based on the characteristics that these cells differentiate and multiply faster than normal cells, so it is inevitable that some normal cells, which also differentiate and multiply faster, will be damaged, causing various adverse reactions, such as damage to hair follicle cells, resulting in hair loss; damage to hematopoietic cells in the bone marrow, resulting in a decrease in white blood cells and platelets; damage to mucosal cells in the gastrointestinal tract, resulting in nausea and vomiting. If the mucous membrane cells of the gastrointestinal tract are damaged, nausea and vomiting will easily occur. These adverse reactions not only affect the quality of life of patients, but also cause interruption of treatment plan if serious, which is extremely unfavorable to the treatment and recovery of lymphoma.