The vector of malaria is Anopheles mosquito, and the main transmission route is through mosquito bites on the skin. Very few cases can develop after importing blood with Plasmodium. Malaria is transmitted by mosquito bites and is difficult to eliminate, especially in some tropical and subtropical regions, such as Africa, where malaria is still endemic. Clinically, malaria can go through four stages: incubation period, chill period, fever period, and sweating period, with symptoms such as repeated intermittent chills, high fever, profuse sweating after the fever subsides, and enlarged liver and spleen. Therefore, patients should actively visit the infection department for reasonable treatment to obtain good treatment results. Patients with malaria should rest in bed, and if their appetite is poor, they can be given liquid or semi-liquid food, and also intravenous rehydration to avoid electrolyte disorders. In life, insecticidal measures should be taken to prevent mosquito bites.