Whether taking 2 tablets of furosemide a day is harmful to the kidneys needs to be judged by factors such as the patient’s condition. If the patient has pre-renal factors leading to acute renal insufficiency, taking 2 tablets of furosemide a day may aggravate the condition, which is harmful to the kidneys at this time; if the patient has edema, nephritis and other diseases, under the guidance of the doctor, the normal dosage of furosemide is not usually harmful to the kidneys. Furosemide is mainly used for the treatment of edematous diseases, hypertension, hyperkalemia and hypercalcemia, dilutional hyponatremia, antidiuretic hormone hypersecretion, acute drug intoxication and other diseases. If patients have pre-renal factors, such as diarrhea and other blood volume insufficiency leading to acute renal insufficiency, if you can’t correct the blood volume in time, taking 2 tablets of furosemide a day may aggravate the condition, and at this time there is a danger to the kidneys; if the patient is treated for other diseases, such as edema, nephritis, etc., under the direction of a doctor, normal dose is usually not hazardous to the kidneys. Common adverse reactions of furosemide include shock, hypokalemia, dizziness, headache, etc. Rarely, there are allergic reactions, hepatic impairment, hyperuricemia, etc. When hypercalcemia is present, it can cause kidney stones. The contraindications of furosemide are not yet clear. If patients need to apply furosemide, it is recommended to use the drug under the guidance of a doctor, not blindly self-medication to avoid adverse effects.