Recently, Beijing’s climate has turned significantly cooler, with temperatures dropping at a greater rate, which has led to a significant increase in the number of patients going to the hospital for treatment of herpes zoster, and the pain clinic of our hospital has been seeing several cases of herpes zoster every day recently. Seasonal changes are prone to herpes zoster, the general public, especially middle-aged and elderly people should pay attention to the combination of work and rest, do not overexertion, so as to avoid the virus to take advantage of the situation. The recent increase in the number of patients with herpes zoster to middle-aged and elderly people, the main cause is the seasonal changes in temperature drop led to a decline in human resistance, while the virus is unusually active, the human body to invade, mainly against the skin and nerves, the skin manifests itself in irregular red spots or blisters, the destruction of nerves lead to the patients feel the lesions of the area of intense pain. This year, 48-year-old Ms. Lai due to the recent busy company business, non-stop running around, people look very tired, two days ago, felt itching, pain in the waist, a closer look and found a string of small blisters on the waist such as a band-like arrangement, and rushed to the Department of Dermatology of Peking University Hospital, after examination was diagnosed as herpes zoster. Herpes zoster is a disease caused by varicella zoster virus, clinically characterized by segmental neuritis and dermatitis. The pain due to neuritis is paroxysmal lightning-like throbbing, sometimes severe and often unbearable. The manifestations of dermatitis are not limited to herpes, but are polymorphic, including erythema, rash, and papules. They may be scattered or clustered, and the number may be large or small, with a small number requiring careful examination to be detected, and sometimes there is even no rash. Herpes zoster is predominantly seen in middle-aged and elderly patients, with those over 40 accounting for almost 3/4 of the cases. generally speaking, the prognosis for the vast majority of patients is good, but older patients can often cause complications in vital organs and the heart and brain, which need to be taken very seriously. The recent increase in the number of patients with herpes zoster is related to the decrease in temperature and the weakening of the body’s resistance, and people should pay attention to prevent it. Work and life should be maintained at an appropriate pace, excessive stress, high tension or excessive fatigue will lead to a decrease in the body’s immunity, coupled with the drop in temperature, the skin’s barrier protection function is weakened, which can easily cause viral infections and the occurrence of herpes zoster. In addition, the diet should pay attention to nutritional balance, light diet, eat more fruits and vegetables, participate in a variety of sports, adjust the physical state. Once a side of the head and face, trunk or limbs of unknown acute pain or accompanied by herpes, should promptly go to the hospital for diagnosis and treatment. The acute stage of herpes zoster is based on anti-virus, nerve nutrition and immunity enhancement. Usually the lesions will heal after half a month or a month, but if the disease lasts more than a month and there is still pain or numbness in the original lesion area, it is postherpetic neuralgia. This requires specialized treatment at a pain clinic.