Oxygen trioxide (O3, also known as ozone and superoxide) is a strong oxidizing agent that destroys proteoglycans in the medullary nucleus matrix, thus causing the nucleus to lose water and atrophy in order to relieve the nerve root compression by the protruding nucleus. In addition, trioxane has the effect of inhibiting the release of painful chemicals and promoting the dissipation of inflammation. Therefore, trioxane injection has become an effective new technique for pain treatment. Scope of application The treatment range of trioxane injection is wide. It is very effective for herniated disc, cervical spondylosis, cervicogenic headache, osteoarthritis, osteophytes, rheumatism, rheumatoid arthritis, spondylitis, herpes zoster, chronic neuralgia, diabetic foot and neck, shoulder, waist and leg pain caused by chronic sterile inflammation. Treatment advantages 1. Minimally invasive treatment, less pain for patients; 2. The decomposition product of trioxane is oxygen, which will not cause damage to organs and tissues; 3. Trioxane can replace hormonal drugs in injection treatment, reducing adverse reactions; 4. Trioxane has strong ability to destroy the nucleus pulposus tissue, but has no obvious adverse effects on the paravertebral tissue; 5. Trioxane has a bactericidal effect, and the incidence of infection after treatment is extremely low; 6. The age adaptation range is wide.