Pimples around the lips may be caused by acne and folliculitis. It is recommended to clarify the diagnosis, give topical medication to apply, and give oral medication if necessary. 1. Acne: Acne can occur on the face, neck, back of shoulders and chest, resulting in localized pimples or inflammatory papules. Treatment options are related to the severity of the disease. Mild cases can be treated with topical application of azelaic acid and adapalene gel. If the inflammation is obvious, if necessary, with oral doxycycline, isotretinoin and other drugs. 2. Folliculitis: Folliculitis is related to bacterial infection and can occur around the mouth. It can be treated with topical mupirocin, erythromycin ointment and other anti-infective treatments. Acne around the mouth do not blindly use drugs, you need to go to the hospital dermatology, combined with the doctor’s advice standardized treatment, the use of drugs need to follow the doctor’s instructions.