Weight loss should be carried out in a scientific way by adjusting the diet combined with exercise, and if necessary, surgery or medication can be used under the guidance of a doctor. 1. Diet should strictly limit the daily energy intake, avoid high-calorie food intake, choose low-salt, low-fat, low-sugar diet, eat more food rich in dietary fiber and protein; exercise can choose aerobic exercise, such as swimming, jogging, jumping rope, and long-term persistence. 2. Drugs are currently only approved for the treatment of obesity, drug therapy for the first 3 months, at least every month should be assessed once the effectiveness and safety of treatment. If the patient loses <5% of body weight in the first 3 months, or if there are safety or tolerability problems at any time, the patient should consider discontinuing the drug and choosing other drugs or treatments. 3. When weight control is still unsatisfactory based on intensive lifestyle intervention and the use of medication, metabolic surgery can be performed under the guidance of a physician. Weight loss should be reasonable and healthy, do not take drugs to lose weight.