Hand shaking may be caused by physiological factors, but also may be a symptom of certain diseases, such as Parkinson’s syndrome, idiopathic tremor, cerebral infarction, etc., and should be promptly consulted to find out the cause. 1. Physiological factors: with the growth of age, the human muscle tissue will undergo different degrees of degradation, especially the elderly, when exertion can occur hand tremor. 2. Pathologic factors (1) Parkinson’s syndrome: this disease is a syndrome with resting tremor, muscle tonus, motor retardation, and loss of postural reflexes, and hand tremor can also occur when exerting oneself. (2) Idiopathic tremor: It is mainly manifested as postural and motor tremor of the hands, head and other parts of the body. Patients have transient tremor during excitement, exertion or fatigue, and they report that their hands shake when they exert themselves, and the amplitude of the tremor may gradually increase with the progress of the disease. (3) Cerebral infarction: Due to the blood circulation disorder in the brain, cerebral tissues of patients with cerebral infarction suffer from ischemia, hypoxia and necrosis, and tremor may occur when the limbs are moving or the hands are exerting themselves, and symptoms such as impaired consciousness, slurred speech, and hemiplegia may also occur. If the hand shakes with force, it is recommended to go to the hospital as soon as possible for examination, and the doctor will give targeted treatment after clarifying the cause of the disease.