Proteinuria does not always develop into uremia, but depends mainly on its primary cause and its type of pathology, etc. Proteinuria refers to total albumin >150 mg in urine within 24 h. Common causes include physiological causes, such as emotional stress and leaner body type in adolescents, which do not require special treatment and usually do not develop into uremia; pathological causes such as urinary tract infection, urinary stones, infection fever and other diseases, which usually disappear after the primary disease is cured. However, when proteinuria occurs in various types of nephritis, nephrotic syndrome, diabetic nephropathy, hypertensive nephropathy and other diseases, the progress of kidney disease will be significantly accelerated, usually the larger the amount of urine protein, the faster the progress of kidney disease, such as diabetic patients with urine protein of 2+, if not treated properly, will develop into uremia within 2-5 years. Patients with proteinuria should choose a high quality low protein diet, actively treat the original disease, and use a combination of Chinese and Western medicine to treat the disease, if the cause of proteinuria is unknown, a kidney puncture biopsy is needed to clarify the diagnosis.