Cymbalta, a common clinical antidepressant, is a dual-receptor antidepressant, a pentraxin reuptake inhibitor, and a norepinephrine reuptake inhibitor. It can effectively improve patients’ low mood, as well as somatic disorders, anxiety, and obsessive-compulsive disorder. Cymbalta is more widely used in clinical practice because of the relatively low side effects. This drug is widely used, especially for patients with somatic disorders, who feel particularly uncomfortable in the body and cannot find any specific problem in the clinical examination, considering anxiety-induced somatic disorders. The application of Cymbalta treatment is quite effective.