Hepatocellular carcinoma requires complete blood biochemistry, ultrasound, CT and MRI examination. 1. Biochemical examination: in blood biochemical examination, alpha-fetoprotein is a specific marker for primary hepatocellular carcinoma, because necrosis with regeneration of hepatocytes will cause elevation of alpha-fetoprotein. Usually, hepatocellular carcinoma will lead to obvious elevation of alpha-fetoprotein, which is beyond the normal range, and in some patients, alpha-fetoprotein can be more than 500ng/mL. 2. Ultrasound: ultrasound examination of hepatocellular carcinoma usually shows heterogeneous mass with unclear boundary and rich blood flow signal. 3. CT: CT often shows uneven density mass shadow with unclear boundary and “fast in and fast out” after enhancement. On magnetic resonance, it often shows equal low signal in T1 and high signal in T2; when necrosis is present, it shows uneven signal, obvious enhancement in arterial phase, and low signal in portal vein phase and delayed phase. When hepatocellular carcinoma is suspected, it is necessary to consult a doctor in time, complete the relevant examination and carry out standardized treatment under the guidance of a doctor.