When a person with a cold has symptoms of coughing up phlegm, the use of expectorant medication can be used to promote the coughing up of phlegm. Colds are a very common respiratory disease, usually caused by viral infections. Symptoms can be relieved by resting, drinking plenty of fluids and eating a light diet. Patients with colds are likely to have phlegm that is too thick to cough up. In this case, patients can effectively dilute or liquefy the phlegm through the use of expectorant medications, such as bromhexine hydrochloride, ammonium chloride, and acetylcysteine, which are commonly used. Cold patients in the phlegm can not cough up, may also be a combination of bacterial infection, bronchitis, pneumonia, etc., when there is a clear bacterial infection, need to use amoxicillin, cefuroxime and other drugs anti-infection treatment. Cold itself is a self-limiting disease, the vast majority of patients can recover on their own without special treatment, but if the symptoms are more serious, you should seek professional medical help, under the guidance of the doctor to use medication. The above medications should be used under the supervision of a physician.