Lupus erythematosus is a connective tissue disease, which is also an autoimmune disease due to increased autoimmune reaction and destruction of its own tissues. China’s medicine believes that the occurrence of this disease, is due to the innate endowment deficiency, kidney essence loss, or due to overwork, five Zhi over extreme, Zhiyu Huo fire, dark depletion of kidney yin, or housework is not in order, the loss of kidney essence due to the loss. Yin deficiency can not moisturize the skin, resulting in important conditions of deficiency, weakened ability to resist disease, the evil evil invasion, the occurrence of this disease. Yin deficiency for a long time, yin loss and Yang, spleen Yang deficiency, transport failure, water and dampness gathered for turbidity; kidney Yang deficiency, the master of the water has no right, the water flood can also be turbid. Water turbidity and blood coagulation in the skin tissue, so the skin edema, erythema, papules and histiocytosis and other pathological changes. The cause of the disease is complex, and it is induced by sun exposure, infection, drugs, exertion, mental trauma, endocrine disorders and other factors. Systemic lupus can also invade the internal organs, causing damage to the heart, lungs, kidneys, digestive system, nervous system, eyes and other organs, resulting in clinical signs and symptoms. Treatment principle: nourish yin and tonify the kidney, diuretic, activate blood circulation and dissipate stagnation, and give equal weight to both positive and evil treatment. Prescription: 40 grams of cooked earth, 10 grams of Cornus officinalis, 12 grams of Qizi, 20 grams of Huayishan, 15 grams of chasteberry, 10 grams of Schisandra chinensis, 9 grams of Dampi, 15 grams of Ophiopogon flexuosus, 50 grams of Xiaku Cao, 14 grams of Xuan Shen, 25 grams of oyster 40 grams of raw oyster (first decoction), 40 grams of sea clam shells (first decoction), 6 grams of Licorice 25 grams of Danshen, decocted in water for two times, twice the combined liquid, a dose per day, divided into three doses. Contraindication: Avoid fish, beef, duck, spicy, tobacco, alcohol and other stimulating products. Addition and subtraction: 1, in the acute attack period, there are high fever, dizziness, delirium, accompanied by hemorrhagic erythema, add honeysuckle 12 grams, dandelion 12 grams, comfrey 10 grams, red peony 12 grams, safflower 6 grams, buffalo horn 25 grams and so on to clear away heat and toxins, cool the blood and eliminate the spots, and at the same time, combine with the treatment of antimicrobial agents. 2.If the disease is of long duration, with prolonged low-grade fever, five heartburn, night sweating, red tongue with little moss, and fine pulse, it is caused by the depletion of yin and blood. Add 15 grams of Zhi Mu, 10 grams of Gentiana Macrophyllae, 15 grams of Bupleurum, 10 grams of Fructus Pelargonifera, and so on, in order to nourish yin and reduce the fire, and to clear the deficiency heat. 3, mental depression, irritability, chest tightness, distension and pain in the ribs, low food intake and dullness, irregular menstruation in women, stringy or stringy pulse, for liver depression and stagnation of qi, it is advisable to dredge the liver and relieve depression, add 7 grams of Chai Hu, 7 grams of Muxiang, 20 grams of Paeoniae Lactiflorae, 10 grams of Yujin, 10 grams of Acorus Pi.