The skin type of lupus erythematosus can be treated with antiphlogistic agents, topical glucocorticoid ointment, and oral drugs such as hydroxychloroquine, aminoglutethimide, tretinoin, and thalidomide. The principle of SLE treatment is to use glucocorticosteroids as early as possible, which should be used early, in sufficient dosage and with a long course of treatment. Early use means that it should be started immediately after diagnosis, while adequate dose means that the starting dose should be large enough, not small dose first and then increase the dose. Long course means that the application time should be long enough to gradually reduce the drug according to the condition, and the drug should generally be used for at least 1 year. Commonly used glucocorticosteroids are prednisone, methylprednisolone, which have short half-lives and do not contain halogenated elements. The dose for adults is every 1-1.5 mg/d/kg. In severe cases, shock therapy with glucocorticoids or shock therapy with immunoglobulins can be used. Immunosuppressive agents such as cyclophosphamide and azathioprine can also be used concurrently, and the drugs should be used under medical supervision.