The most significant biochemical feature of Parkinson’s disease is the reduction of striatal dopamine content in the brain, while dopamine and acetylcholine are the two most important neurotransmitters in the striatum, and the functions of these two transmitters are mutually antagonistic. The principle is to supplement the striatal dopamine in the brain, which is effective for normal muscle tonicity and motor retardation; 2, dopamine receptor agonists: clinically used are piribedil, pramipexole, bromocriptine, etc. The principle is to stimulate the postsynaptic membrane dopamine receptors; 3, anticholinergic drugs: clinically used are benzhexol, etc. These drugs are effective for tremor and muscle tonicity, but less effective for motor retardation; 4, amantadine: mainly to promote The pharmacological mechanism is to inhibit the catabolism of dopamine in neurons and enhance the content of dopamine in the brain; 6, catechol-oxo- methyltransferase inhibitors: such as entocapone, tolcapone, etc. The pharmacological mechanism is to inhibit the metabolism of levodopa in the periphery and maintain the levodopa plasma The pharmacological mechanism is to inhibit levodopa metabolism in the periphery and maintain stable levodopa plasma concentration to increase the amount of dopamine in the brain; 7. Other classes, such as coenzyme Q10, neuroprotective agents, etc.: clinically, a variety of use programs are often developed according to the age of onset, whether there is any diminished intelligence and related conditions, side effects, drug interactions, economic ability, etc., and need to be applied under the guidance of a senior professional physician. On the other hand, Chinese medicine can also play an important role in the treatment of Parkinson’s disease. The rational application of Chinese medicine can reduce the dosage of western drugs and alleviate side effects. Chinese medicine believes that the disease is caused by wind and yang, insufficient marrow, deficiency of qi and blood, or phlegm and heat that move wind, and certain prescriptions can be used to nourish the liver and kidney, calm the liver and submerge the yang, benefit qi and blood, and clear heat and phlegm.