The difference between common cold and influenza mainly lies in the pathogens, symptoms, characteristics, treatment and other aspects. 1. Pathogens: The pathogens of common cold are mainly rhinovirus, adenovirus, coronavirus, etc. The pathogens of influenza are mainly influenza virus. 2. Symptoms: The common cold is mild and the systemic symptoms are not serious, usually showing upper respiratory tract symptoms such as nasal congestion, runny nose, cough and so on. Influenza, on the other hand, is more serious, with heavy systemic symptoms, fever, body aches, weakness of the limbs and other manifestations, while the upper respiratory tract symptoms are mild. 3. Characteristics: The common cold is somewhat contagious, but generally does not break out in epidemic proportions. Influenza, on the other hand, is epidemic due to its high mutation rate and general susceptibility of the population. 4. Treatment: The common cold is mainly symptomatic, and generally does not require antiviral treatment. On the other hand, influenza requires the use of antiviral drugs such as oseltamivir at an early stage. If the patient has symptoms related to cold and flu, and the symptoms are more serious, it is recommended to consult a doctor in time and standardize the treatment.