The number of patients with cranial defects has gradually increased in recent years, especially in recent years when various traffic accidents, production safety accidents and accidental injuries have occurred frequently, and the number of traumatic cranial defects caused by these accidents has also gradually increased. Cranial defects not only bring a large mental burden to patients, but also require cranial repair because the brain tissue lacks a complete cranial protective barrier and is prone to injury and a series of secondary symptoms. The repair of traumatic cranial defects is gradually gaining attention from neurosurgeons. In neurosurgical guidelines, patients with cranial defects due to debridement, generally 3-4 months after the defect, with a defect area of 3*3 cm or more, are eligible for surgery and patients need to go to the hospital for repair by specialized surgeons. Cranial repair is a common surgery, the implementation of which is not difficult and can be carried out in large hospitals in general, as long as the scalp is cut open, the periosteum is bluntly separated, the bone window is completely exposed, the repair prosthesis is placed in the bone window and adjusted to achieve physiological anatomical reset, and the skin is sutured layer by layer. The results vary greatly depending on the surgical approach taken and the expertise of the surgeon. Over time, repair materials have become more and more advanced and closer to the standard. From the flannel sheet covering the bone window repair thousands of years ago, to the metal sheet, plexiglass, light apatite and calcium phosphate bone cement, and then to the titanium mesh material which was widely used clinically in the previous period, it can be said that there has been a continuous progress. But these materials always have such and such problems, and not to achieve the very ideal effect. Currently, the new material polyether ether ketone, also known as PEEK material, is widely favored by medical experts, and we use peek material for skull repair. First of all, PEEK material is very biocompatible, no rejection, and does not affect the postoperative medical examinations. In addition, it is comparable to autologous cranial bone in terms of strength, stiffness, elasticity, and thermal insulation, and more importantly, it can perfectly restore the physiological structure of the skull by preoperative three-dimensional shaping according to the patient’s cranial data.