Urinary NAG enzyme 22.5 U/L is higher than normal value, its seriousness depends mainly on the cause of its elevation, and cannot be generalized. Urinary NAG enzyme is called urinary N-acetyl β-D aminoglucosidase, and the common causes of elevation are renal tubular injury, acute glomerulonephritis, nephrotic syndrome and so on.
1. Renal tubular injury: If there is necrosis of renal tubules or poisoning of renal tubules, it may lead to elevation of urinary NAG enzyme. If treated in time, it is usually not serious.
2. Acute glomerulonephritis: Clinical manifestations include hematuria, proteinuria, edema, hypertension, transient renal insufficiency and other symptoms, and elevated urinary NAG enzyme can occur. This disease is a self-limiting disease, most patients have a good prognosis, and it is not serious at this time.
3. Nephrotic syndrome: it is a clinical syndrome composed of glomerular diseases with different etiology and pathology, which can cause renal function damage and elevated urinary NAGase. If the condition is mild and the treatment effect is good, it is usually not serious. If the condition is severe and the treatment effect is poor, with the progress of the condition, it may develop into chronic renal failure, which is more serious at this time.
If patients find that the urine NAG enzyme is elevated, it is recommended to go to the regular hospital in time, improve the examination to clarify the cause of the disease, and under the guidance of the doctor to give targeted treatment or therapy.