Antiphospholipid antibody syndrome is a clinical syndrome characterized by recurrent thrombotic events and miscarriages, accompanied by the presence of serum antiphospholipid antibodies. The clinical manifestations are mainly thrombosis, which is most prevalent in small and medium-sized vessels, and thrombosis can occur in both arteries and veins, with venous thrombosis being more common.
Antiphospholipid antibodies are a group of autoantibodies against lupus anticoagulant substances, anticardiolipin antibodies, or against other phospholipids or phospholipid complexes. The most basic pathologic feature of antiphospholipid antibody syndrome is thrombosis, with which all clinical manifestations are associated.
Clinically, it can be divided into primary antiphospholipid antibody syndrome and secondary antiphospholipid antibody syndrome, which can be secondary to connective tissue diseases such as systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, and dry syndrome.
It is recommended that patients with antiphospholipid antibody syndrome go to the hospital in time and receive standardized diagnosis and treatment under the guidance of doctors.